Some recent developments in the preparation of novel recognition systems: A recognition site for the selective catalysis of an aldol condensation using molecular imprinting and specific affinity motifs for α-chymotrypsin using a phage display peptide libr
- 1 October 1996
- journal article
- Published by Wiley in Journal of Molecular Recognition
- Vol. 9 (5-6) , 652-657
- https://doi.org/10.1002/(sici)1099-1352(199634/12)9:5/6<652::aid-jmr316>3.0.co;2-6
Abstract
Molecular imprinting and phage display library technologies are rapidly being accepted as useful techniques for the generation of ligand‐selective recognition motifs. The use of molecular imprinting to produce a novel type II aldolase mimic selective for the cobalt(II)‐mediated aldol condensation of benzophenone and acetaldehyde is reported here. Furthermore, peptide motifs have been identified which are acting as 'affinity ligands' selective for the recognition of the enzyme α‐chymotrypsin using phage display techniques.Keywords
This publication has 21 references indexed in Scilit:
- Molecular imprinting: A technique for producing specific separation materialsPublished by Elsevier ,2004
- Mimics of the binding sites of opioid receptors obtained by molecular imprinting of enkephalin and morphine.Proceedings of the National Academy of Sciences, 1995
- Antibody Mimics Obtained by Noncovalent Molecular ImprintingPublished by American Chemical Society (ACS) ,1995
- Selection of Peptides with Affinity for Single-Stranded DNA Using a Phage Display LibraryBiochemical and Biophysical Research Communications, 1994
- Tools of the Trade Combinatorial Libraries: Finding the needle in the haystackCurrent Biology, 1994
- In vitro selection of zinc fingers with altered DNA-binding specificityBiochemistry, 1994
- In vitro selection from protein and peptide librariesTrends in Biotechnology, 1994
- Molecular imprinting—a versatile technique for the preparation of separation materials of predetermined selectivityPublished by Springer Nature ,1994
- Direct enantioseparation of .beta.-adrenergic blockers using a chiral stationary phase prepared by molecular imprintingJournal of the American Chemical Society, 1991
- Peptides on phage: a vast library of peptides for identifying ligands.Proceedings of the National Academy of Sciences, 1990