Pyruvate oxidation in brain
- 1 October 1938
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 32 (10) , 1711-1717
- https://doi.org/10.1042/bj0321711
Abstract
Incomplete oxidation of pyruvic acid is known to occur when pigeon brain brei respires in pyruvate solns. At pH 7.3, and 38[degree], the O2/pyruvate ratio is 450 [mu]l./mg. (theoretical for complete oxidation, 635). Acetic acid (24.8%) and lactic acid (52%) have been found to arise under these conditions. These amts. account quantitatively for the disappearance of pyruvic acid. The final balance sheet satisfactorily explains the high recorded value for the R.Q., 1.30, as compared with the theoretical of 1.20 for complete oxidation.This publication has 9 references indexed in Scilit:
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