URINARY EVALUATION OF 5-S-CYSTEINYLDOPA AND SERIC EVALUATION OF IGG4 SUBCLASS DURING FOLLOW-UP OF 27 PRIMITIVE MALIGNANT MELANOMAS

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 105  (4) , 405-408
Abstract
Twenty-seven patients with SSM [superficial spreading melanoma] or NM [nodular melanoma] level IV and V were submitted to a monthly evaluation of their level of 5-S-cysteinyldopa[5S] in the urine and IgG4 [immunoglobulin G4] subclass in their sera. For 5 patients who entered stage II of their disease during the follow-up, 3 had elevation of 5S and 5 had large variations of IgG4. Of 21 patients in clinical remission, 10 had an increase of 5S and variations of IgG4. The predictive value of these tests is discussed.

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