VirusMINT: a viral protein interaction database
Open Access
- 30 October 2008
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 37 (Database) , D669-D673
- https://doi.org/10.1093/nar/gkn739
Abstract
Understanding the consequences on host physiology induced by viral infection requires complete understanding of the perturbations caused by virus proteins on the cellular protein interaction network. The VirusMINT database (http://mint.bio.uniroma2.it/virusmint/) aims at collecting all protein interactions between viral and human proteins reported in the literature. VirusMINT currently stores over 5000 interactions involving more than 490 unique viral proteins from more than 110 different viral strains. The whole data set can be easily queried through the search pages and the results can be displayed with a graphical viewer. The curation effort has focused on manuscripts reporting interactions between human proteins and proteins encoded by some of the most medically relevant viruses: papilloma viruses, human immunodeficiency virus 1, Epstein–Barr virus, hepatitis B virus, hepatitis C virus, herpes viruses and Simian virus 40.Keywords
This publication has 10 references indexed in Scilit:
- Protein interactions: integration leads to beliefTrends in Biochemical Sciences, 2008
- Linking entries in protein interaction database to structured text: The FEBS Letters experimentFEBS Letters, 2008
- The Landscape of Human Proteins Interacting with Viruses and Other PathogensPLoS Pathogens, 2008
- The Universal Protein Resource (UniProt)Nucleic Acids Research, 2007
- The Protein Identifier Cross-Referencing (PICR) service: reconciling protein identifiers across multiple source databasesBMC Bioinformatics, 2007
- Broadening the horizon – level 2.5 of the HUPO-PSI format for molecular interactionsBMC Biology, 2007
- The minimum information required for reporting a molecular interaction experiment (MIMIx)Nature Biotechnology, 2007
- IntAct--open source resource for molecular interaction dataNucleic Acids Research, 2006
- MINT: the Molecular INTeraction databaseNucleic Acids Research, 2006
- Extraction of protein interaction information from unstructured text using a context-free grammarBioinformatics, 2003