THE EXCRETION OF URINE IN THE DOG

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Abstract
The results of 22 experiments on 3 dogs indicate that the urea and creatinine clearances, as determined 16-18 hrs. after the last meal, are reduced to low levels in dogs which are either fasted or fed upon a protein-poor diet composed of cracker meal, lard and sugar. The substitution of a mixed diet produces a marked elevation of the urea and creatinine clearances, and the substitution of an exclusive meat diet increases both clearances more than 100%. This effect is not related to the absolute amt. of urea excreted. The urea clearance shows more uniformity on a low protein cracker meal diet than on a mixed diet. The augmentation limit appears to be lower on a cracker meal than on a mixed diet in proportion to the lowering of the maximal clearance.

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