A New Synthesis of 2-Substituted DL-Tryptophan Derivatives
- 1 April 1995
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1995 (04) , 370-372
- https://doi.org/10.1055/s-1995-3915
Abstract
Methyl 2-substituted N-(diphenylmethylene)-DL-tryptophanates were prepared by means of Lewis acid catalysed Michael-type addition of methyl N-(diphenylmethylene)dehydroalaninate to suitable 2-substituted indoles. Hydrolysis of these tryptophan derivatives affords the corresponding amino acids. Examples of selective deprotection of either the amino or carboxylic group are reported.Keywords
This publication has 0 references indexed in Scilit: