Histology of Benign Virus Induced Tumors of the Skin

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Abstract
The majority of findings in relation to warts were passed on from 1 textbook to the other since the end of the last century. More recent studies were carried out by EM. Information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, the interference microscope, microradiography and other new techniques. Warts are a proliferation of the epidermis caused by a virus, which acts in the epidermis itself. Warts are acanthomas, and a transition to malignancy is possible in predisposed persons. In the malignant tumors of epidermodysplasia verruciformis, no virus could be found. As the demonstration of viruses by EM and other techniques cannot be made as a matter of routine, a simpler method with the light microscope must be found. With the application of more elaborate procedures, new information about epidermal proliferation should be obtained.