Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells
- 1 January 2000
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 14 (1) , 65-77
- https://doi.org/10.1096/fasebj.14.1.65
Abstract
Proteolysis mediated by the ubiquitin-proteasome system has been implicated in the regulation of programmed cell death. Here we investigated the differential effects of proteasomal inhibitors on th...Keywords
This publication has 60 references indexed in Scilit:
- Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrestOncogene, 1999
- The Proteasome Is Involved in AngiogenesisBiochemical and Biophysical Research Communications, 1998
- Lactacystin, a Specific Inhibitor of the Proteasome, Inhibits Human Platelet Lysosomal Cathepsin A-like EnzymeBiochemical and Biophysical Research Communications, 1997
- Mechanism of p53 degradationBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1997
- Enhancement of CPP32-like Activity in the TNF-Treated U937 Cells by the Proteasome InhibitorsBiochemical and Biophysical Research Communications, 1996
- Lactacystin, a Specific Inhibitor of the Proteasome, Induces Apoptosis in Human Monoblast U937 CellsBiochemical and Biophysical Research Communications, 1995
- Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivoNature, 1993
- Induction of apoptosis in fibroblasts by c-myc proteinCell, 1992
- Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell deathNature, 1990
- Embedding in Epoxy Resins for Ultrathin Sectioning in Electron MicroscopyStain Technology, 1960