Abstract
Summary: A direct comparison was made in 112 hay fever patients of hyposensitization treatment with glutaraldehyde‐pollen‐tyrosine adsorbate (Pollinex) and with alum‐precipitated pyridine extract (Alavac‐P) which is an accepted form of treatment, its efficacy having been shown by a comparative trial against a placebo preparation.No significant difference could be detected between the results of the two forms of treatment. Seventy‐seven per cent of patients responded with improvement following treatment with the tyrosine adsorbed vaccine, and 81% of those receiving the alum‐precipitated vaccine. Side effects from treatment, both local and general, were generally of an infrequent or mild nature for both vaccines.