An 18-month Followup of Students Biologically at Risk for Psychiatric Problems

Abstract
A prospective investigation using platelet monoamine oxidase activity and cortical evoked response augmenting/reducing to predict the onset of new episodes of affective disorders was conducted in a college sample. During an 18-month period between clinical interviews, higher incidences of major depression and hypomania characterized the low MAO/augmenting and the high MAO/reducing subjects. These same subgroups also had been associated with affective psychopathology in the original retrospective study.

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