Diurnal Variation of Intraocular Pressure and the Overriding Effects of Sleep
- 1 January 1987
- journal article
- research article
- Published by Wolters Kluwer Health in Optometry and Vision Science
- Vol. 64 (1) , 54-61
- https://doi.org/10.1097/00006324-198701000-00010
Abstract
Intraocular pressure (IOP) was recorded regularly over a 24-h period in 13 normal subjects. All subjects showed a dramatic rise in IOP after sleep, ranging from 37 to 248%. In a second experiment, IOP decreased when 15 subjects remained upright and awake throughout the night. When sleep was not permitted IOP was lowest at 3:00 a.m. (0300); when six of these subjects were permitted to sleep from 0600 to 0800, they showed a rapid and significant increase in IOP of up to 150%, whereas the remaining nine subjects showed (posturally induced) increases of up to 38%.Keywords
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