Abstract
The hemolytic reaction to infection with hemolytic streptococci and intoxication with streptolysin was studied in the rabbit, using Sjostrand''s method for the determination of the intravital CO production. Injection of streptolysin is accompanied by an increase in CO production, which seems to be a manifestation of increased hemolysis. During infection with hemolytic streptococci a slight increase in CO production can be demonstrated but, on the other hand, there is an altered reaction pattern on the injection of streptolysin which cannot be explained on the ground of antistreptolysin production.

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