IMPROVEMENT OF CELL IMMUNITY INDEXES UNDER INFLUENCE OF POLYPEPTIDE EPIPHYSEAL EXTRACT (EPITHALAMINE)

  • 1 January 1977
    • journal article
    • research article
    • Vol. 23  (6) , 7-9
Abstract
Pineal polypeptide factors enhance the sensitivity of the hypothalamo-hypophyseal complex to the inhibiting action of glucocorticoids and estrogens, show an antistressor effect and the capacity to decrease the level of insulin and triglycerides in the experiment and also suppress the growth of transplantable [rat] mammary gland cancer. The pineal polypeptide extract was employed in a patient with reduced indices of cellular immunity. A restoration of indices of blast-transformation reaction induced by phytohemagglutinin, an increased number of rosette-forming cells and an improved response to dinitrochlorobenzene skin test were noted.

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