Mouse Soleus Muscle Na-K Pump Activity: Direct Correlation with In Vitro and In Vivo Oxygen Consumption
- 1 November 1986
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 18 (11) , 757-760
- https://doi.org/10.1055/s-2007-1012428
Abstract
To evaluate the contribution of active sodium-potassium transport to energy utilization, measurements of sodium-potassium pump activity in isolated soleus muscles of normal mice were carried out and related to measurements of oxygen consumption by the tissue. A highly significant positive correlation (r = 0.89, p < 0.001) was found between these two parameters. In addition, both the in vitro oxygen consumption and Na-K pump activity of the muscles were found to correlate with whole body oxygen utilization by the experimental animals. The results support a role for the sodium-potassium pump in the determination of energy turnover.Keywords
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