Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestinal epithelial cells.
Open Access
- 1 June 1986
- journal article
- abstracts
- Published by Elsevier
- Vol. 261 (18) , 8348-8356
- https://doi.org/10.1016/s0021-9258(19)83919-4
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Effects of 3.beta.-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell culturesBiochemistry, 1983
- Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes.Journal of Clinical Investigation, 1983
- Enzymic reduction of an epoxide to an alcoholJournal of the American Chemical Society, 1982
- Post-HMG CoA reductase regulation of cholesterol biosynthesis in normal human lymphocytes: Lanosten-3β-ol-32-al, a natural inhibitorBiochemical and Biophysical Research Communications, 1981
- Sterol BiosynthesisAnnual Review of Biochemistry, 1981
- Mechanism of Action of Antifungal Drugs, with Special Reference to the Imidazole DerivativesClinical Infectious Diseases, 1980
- IntroductionClinical Infectious Diseases, 1980
- Biological Activity of Some Oxygenated SterolsScience, 1978
- Cholesterol, 7-ketocholesterol and 25-hydroxycholesterol uptake studies and effect on 3-hydroxy-3-methylglutaryl-coenzyme a reductase activity in human fibroblastsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1975
- The plurality of long chain isoprenoid alcohols (polyprenols) from natural sourcesBiochimica et Biophysica Acta (BBA) - General Subjects, 1967