In vivo antibacterial effect of tin on the oral microflora

Publisher Website
Google Scholar
Abstract
The antibacterial effect of oral rinses with stannous fluoride and stannous chloride solutions, and of the use of a toothpaste containing stannous fluoride and stannous pyrophosphate was tested by recording the bacterial viable counts on the [human] oral mucous membrane. Stannous chloride had no antibacterial effect, while stannous fluoride drastically reduced the viable counts up to 4 h. Calculations demonstrated that 25% of the Sn content in 10 ml rinsing solutions was retained in the month, and analyses showed a raised Sn level in saliva up to 4 h after rinsing or toothbrushing. Most of the retained Sn is apparently bound to the oral mucosa.