Blastogenic transformation by lipopolysaccharide of blood leukocytes from immunized but not normal cattle

Abstract
Escherichia coli lipopolysaccharide produced blastogenic transformation in whole-blood leukocytes from heifers infected and immunized with Campylobacter fetus, but not in cells from control animals. Apparently lipopolysaccharide does not function as a B[bone marrow derived]-cell mitogen in cattle and its stimulation of cells from immunized animals occurred through another mechanism.