Suppressing effect of thioanisole on a side reaction during the acidolytic cleavage of protecting groups of tyrosine.

Publisher Website
Google Scholar
Abstract
The use of thioanisole as a scavenger was found to suppress a side reaction when the O-protecting groups of tyrosine were deblocked under the acidic conditions. This good result gives a promising outlook for the synthesis of tyrosine-containing peptides by solid-phase method.