Abstract
The synthesis and aqueous complexation behaviour of C- and N-linked o-hydroxyaryl substituted derivatives of 1,5,9-triazacyclododecane is reported. The N-linked ligand forms strong 1:1 complexes with copper and zinc (log KML= 18.7 and 14.1, respectively) in which the phenolate acts as an effective donor ligand in the putative tetrahedral complex. The ligand substituted at carbon at the 3-position is less basic and forms much weaker complexes with Cu2+, Ni2+ and Zn2+(log KCuL, 10.2, log KZnL 7.32 and log KNiL 6.11) in which phenolate participation is absent.

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