Effect of synthetic thyrotrophin-releasing hormone and its analogues on growth hormone secretion in the domestic fowl (Gallus Domesticus)
- 1 August 1981
- journal article
- research article
- Published by Bioscientifica in Acta Endocrinologica
- Vol. 97 (4) , 448-453
- https://doi.org/10.1530/acta.0.0970448
Abstract
Variations in plasma growth hormone (GH) concentrations following iv or sc administration of synthetic thyrotrophin-releasing hormone (TRH, Pyr-His-Pro-NH2) have been followed in immature and adult domestic fowl. TRH markedly stimulated GH secretion in newly hatched (1 and 2 day old) chicks and in 6-week-old cockerels but in adult male or female birds of two strains had very little effect, if any. Intravenous injection of 4 TRH analogues (Pyr-His-Mep-NH2, Pyr-Meh-Mep-NH2, Pyr-Meh-Mep-NH and Pyr-Meh-Pro-NH2) were also potent GH secretagogues in 6-week-old birds. The stimulatory effect of TRH or the TRH-analogues on GH secretion was not dose-related.This publication has 13 references indexed in Scilit:
- Growth Hormone Releasing Activity of Thyrotropin-Releasing Hornione in Rats with Hypothalamic Lesions12Endocrinology, 1977
- Growth Rate and Secretion of Pituitary Hormones in Relation to Age and Chronic Treatment with Thyrotropin-Releasing Hormone in Prepubertal Dairy HeifersEndocrinology, 1977
- PURIFICATION AND RADIOIMMUNOASSAY OF CHICKEN GROWTH HORMONEJournal of Endocrinology, 1977
- Release of Growth Hormone by TRH in Intact Rats or in Intact or Hypophysectomized Rats bearing a Heterotopic PituitaryExperimental Biology and Medicine, 1977
- Growth, Serum Growth Hormone, Thyroxine, Prolactin and Insulin in Calves after Thyrotropin Releasing Hormone or 3-Methyl-Thyrotropin Releasing HormoneJournal of Animal Science, 1977
- THYROTROPHIN RELEASING HORMONE-INDUCED GROWTH HORMONE AND PROLACTIN RELEASE: PHYSIOLOGICAL STUDIES IN INTACT RATS AND IN HYPOPHYSECTOMIZED RATS BEARING AN ECTOPIC PITUITARY GLANDJournal of Endocrinology, 1977
- Effects of Hyperthyroidism and Hypothyroidism on Rat Growth Hormone Release Induced by Thyrotropin-Releasing HormoneEndocrinology, 1976
- Influence of Chronic Thyrotropin-Releasing Hormone Injections on Secretion of Prolactin, Thyrotropin and Growth Hormone and on Growth Rate in Wether LambsJournal of Animal Science, 1976
- Stimulation of Growth Hormone Release by Thyrotropin-Releasing Hormone in the Hypophysectomized Rat Bearing an Ectopic PituitaryEndocrinology, 1976
- Altered Growth Hormone and Prolactin Responsiveness to TRH in the Infant RatNeuroendocrinology, 1976