PROBABLE MECHANISM OF SPLEEN COLONY FORMATION SUPPRESSION WITH RABBIT ANTI-MOUSE BRAIN ANTISERUM

  • 1 January 1980
    • journal article
    • research article
    • Vol. 8  (10) , 1216-1221
Abstract
Syngeneic thymocytes restore the capacity of bone marrow treated with rabbit antimouse brain (RAMB) serum to form the spleen colonies. The same effect may be exerted by the V fraction of thymosin or endotoxin, but not by allogeneic thymocytes. RAMB serum apparently acts not on the stem cells but on another cell population (accessory cells?) contributing to the differentiation.