Characteristics of redox‐linked proton ejection in cytochrome c oxidase reconstituted in phospholipid vesicles
Open Access
- 27 June 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 157 (1) , 7-14
- https://doi.org/10.1016/0014-5793(83)81106-5
Abstract
Experimental observations reveal a number of characteristics of the redox‐linked proton ejection from cytochrome c oxidase vesicles, which apparently cannot be explained by a proton pumping activity of the oxidase. These observations seem, on the other hand, to provide useful elements for alternative explanation(s) of the proton ejection. It is proposed here that the process is scalar and not vectorial and can derive from redox‐linked rupture of protonated salt‐bridges in the oxidase‐lipid complex.Keywords
This publication has 29 references indexed in Scilit:
- Mechanism of proton translocation associated to oxidation of N,N,N′,N′‐tetramethyl‐p‐phenylenediamine in rat liver mitochondriaFEBS Letters, 1983
- Alternative hypotheses of proton ejection in cytochrome oxidase vesiclesFEBS Letters, 1983
- On the inhibition of the bc1 segment on the mitochondrial respiratory chain by quinone analogues and hydroxyquinoline derivativesFEBS Letters, 1982
- Critical evaluation of the proton‐translocating property of cytochrome oxidase in rat liver mitochondriaFEBS Letters, 1982
- Purification and Characterization of the CytochromecOxidase fromRhodopseudomonas sphaeroidesEuropean Journal of Biochemistry, 1982
- Redox Bohr‐effects in isolated cytochrome bc1 complex and cytochrome c oxidase from beef‐heart mitochondriaFEBS Letters, 1981
- Cytochrome c oxidase: Towards a clarification of its structure, interactions and mechanismBiochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1980
- Functional studies on crosslinked bovine cytochrome c oxidaseFEBS Letters, 1978
- The mechanism of energy conservation and transduction by mitochondrial cytochrome c oxidaseBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1977
- Proton translocation reactions in the respiratory chainsBiochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1976