SURVIVAL OF T PALLIDUM UNDER MICROAEROBIC CONDITIONS IN CELL AND TISSUE-CULTURES

  • 1 January 1976
    • journal article
    • research article
    • Vol. 235  (4) , 500-505
Abstract
The survival of pathogenic Treponema pallidum was studied under microaerobic conditions (partial pressure of O2 7 mm Hg) with and without tissue cell cultures. As 1/3-1/2 of the germs were motile even after 96 h incubation, treponemes do not seem to be strictly anerobic as has been generally believed. Flocs containing enormous numbers of treponemes were observed in the nutrient medium. For their formation, human serum, testicular components from rabbits and modified survival medium were essential. Although the problem of cultivation of T. pallidum remains, the formation of flocs indicates a possible transient multiplication of treponemes in vitro.

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