MATURATION OF POLIOVIRUS RNA WITH CAPSID PROTEIN CODED BY HETEROLOGOUS ENTEROVIRUSES

Abstract
Under certain in vivo conditions of double infection, the protein capsid of a replicating type 2 poliovirus or B1 Coxsackie virus enclosed the RNA of type 1 poliovirus to form millions of mature "hybrid" virus particles whose immunologic phenotype differed from their genotype.