Difference of Serum Levels of Type IV Collagen 7S between Early or Overt Nephropathy and Nondiabetic Renal Disease in Diabetic Patients with Micro- or Macroalbuminuria
- 1 January 1996
- journal article
- clinical trial
- Published by S. Karger AG in Nephron
- Vol. 73 (4) , 601-605
- https://doi.org/10.1159/000189147
Abstract
We determined serum levels of type IV collagen 7S (IV 7S) in 73 (23 with normoalbuminuria, 21 with microalbuminuria, 17 with macroalbuminuria, and 12 primarily affected by nondiabetic renal disease (NDRD)) and 24 (10 with only macroangiopathy and 14 with retinopathy and macroangiopathy) diabetic patients to see whether IV 7S can be a useful index for differentiating early or overt diabetic nephropathy from NDRD in micro or macroalbuminuric diabetics. IV 7S was significantly elevated in diabetic patients with micro-or macroalbuminuria compared to those with normoalbuminuria and healthy controls (pKeywords
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