The efficacy of a parent infant training program was evaluated in terms of a number of subject-related variables (i.e., sex, severity, age). Data collected on 32 high-risk infants, over a 1-year time span, showed substantial gains on both cognitive and language indices. However, the relative degree of success on these measures was related to the initial age and initial severity of the infants under study. The results are discussed in terms of effective early intervention strategies which employ parents as the primary intervention agents for high-risk infants.