Specific Precipitin Bands in the Serology of Histoplasmosis1

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Abstract
The patients with active histoplasmosis reported here were not severely ill on entering the hospital. Attempts to culture the fungus from exudates and biopsies by direct methods and mouse inoculations were unsuccessful, and histopathology failed to reveal the organisms. Diagnosis had to be made on clinical and serologic evidence. Under these circumstances the plate precipitin test, using antigen which demonstrated M and H bands, in addition to the complement-fixation titers, adds another parameter to the evaluation of the state of activity of Histoplasma infection.

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