CpG oligonucleotides: novel regulators of osteoclast differentiation
Open Access
- 14 January 2002
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 16 (3) , 274-282
- https://doi.org/10.1096/fj.01-0586com
Abstract
The macrophage capability to recognize bacterial DNA is mimicked by oligodeoxynucleotides containing unmethylated CG dinucleotides (‘CpG’ motifs) in specific sequence contexts (CpG ODN). CpG ODN stim...Keywords
Funding Information
- German-Israeli Foundation for Scientific Research and Development
This publication has 32 references indexed in Scilit:
- Tumor necrosis factor‐α mediates RANK ligand stimulation of osteoclast differentiation by an autocrine mechanism†Journal of Cellular Biochemistry, 2001
- Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cellsEuropean Journal of Immunology, 2001
- TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligandJournal of Clinical Investigation, 2000
- Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and ActivationCell, 1998
- Requirement for NF-κB in osteoclast and B-cell developmentGenes & Development, 1997
- Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shockEuropean Journal of Immunology, 1997
- Immune Activation by Bacterial DNA: A New Genetic CodeImmunity, 1996
- CpG motifs in bacterial DNA trigger direct B-cell activationNature, 1995
- Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice.Journal of Clinical Investigation, 1994
- Regulation of TNF‐α release from bone marrow–derived macrophages by vitamin DJournal of Cellular Biochemistry, 1994