Collateral regeneration in partially denervated muscles

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Abstract
The author briefly reviews the evidence in support of the concept that surviving motor nerve fibers in partially-denervated human muscles are capable of branching and reinnervating adjacent denervated fibers. This process is accompanied by an increase in size of the remaining motor units, and this may explain the increase in duration and amplitude of action potentials in these muscles. Explanations of other clinical and electromyographic phenomena in partially denervated muscles in terms of collateral regeneration are also considered.