Effect of Amlodipine on Morbidity and Mortality in Severe Chronic Heart Failure
Open Access
- 10 October 1996
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 335 (15) , 1107-1114
- https://doi.org/10.1056/nejm199610103351504
Abstract
Previous studies have shown that calcium-channel blockers increase morbidity and mortality in patients with chronic heart failure. We studied the effect of a new calcium-channel blocker, amlodipine, in patients with severe chronic heart failure.Keywords
This publication has 24 references indexed in Scilit:
- Placebo controlled trial of felodipine in patients with mild to moderate heart failure. UK Study Group.Heart, 1995
- Management of patients with heart failure and angina: Do coexistent diseases alter the response to cardiovascular drugs?Journal of the American College of Cardiology, 1991
- Diltiazem increases late-onset congestive heart failure in postinfarction patients with early reduction in ejection fraction. The Adverse Experience Committee; and the Multicenter Diltiazem Postinfarction Research Group.Circulation, 1991
- A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure.Circulation, 1990
- The Effect of Diltiazem on Mortality and Reinfarction after Myocardial InfarctionNew England Journal of Medicine, 1988
- Prognostic importance of the immediate hemodynamic response to nifedipine in patients with severe left ventricular dysfunctionJournal of the American College of Cardiology, 1987
- Felodipine in patients with chronic heart failure: discrepant haemodynamic and clinical effects.Heart, 1987
- Chronic renal and neurohumoral effects of the calcium entry blocker nisoldipine in patients with congestive heart failureJournal of the American College of Cardiology, 1987
- Discrete Sequential Boundaries for Clinical TrialsBiometrika, 1983
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958