A Review of Ondansetron in the Management of Radiotherapy-Induced Emesis
- 1 January 1993
- journal article
- case report
- Published by S. Karger AG in Oncology
- Vol. 50 (3) , 173-179
- https://doi.org/10.1159/000227173
Abstract
This paper reviews experience with ondansetron in radiotherapy-induced emesis. The efficacy of ondansetron is assessed following a number of different radiotherapy regimens: single-dose radiotherapy, fractionated radiotherapy, total body irradiation (TBI) and hemi-body irradiation. In single-dose radiation-induced emesis, ondansetron (8 mg orally 3 times daily) provided superior anti-emetic control compared with metoclopramide (10 mg orally 3 times daily): 92 and 46% of patients, respectively, experienced complete control of emesis (0 emetic episodes) in the first 24 h following treatment (pKeywords
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