Acetaminophen Poisoning in Infancy
- 1 April 1983
- journal article
- case report
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 137 (4) , 386-387
- https://doi.org/10.1001/archpedi.1983.02140300064018
Abstract
• Acetaminophen is widely used in children of all ages, and overdosage from this medication is common. Although severe hepatotoxicity from overdosage occurs in adults, acetaminophen seems to have a wide margin of safety in younger children. This has been ascribed to altered pharmacokinetics in this age group. We report two cases in which severe acetaminopheninduced hepatotoxicity occurred in two infants. Neither infant reportedly received potentially toxic dosages, by history, but toxic drug levels were present in both. (Am J Dis Child 1983;137:386-387)Keywords
This publication has 3 references indexed in Scilit:
- Chronic Excessive Acetaminophen Use and Liver DamageAnnals of Internal Medicine, 1977
- Age-related differences in salicylamide and acetaminophen conjugation in manThe Journal of Pediatrics, 1977
- How Safe is Acetaminophen?Clinical Pediatrics, 1973