Inhibition of Aflatoxin-Induced Serum -Fetoprotein in Rats Fed Cauliflower

Abstract
The highly sensitive competitive binding radioimmunoassay showed an increased level of serum AFP [d-fetoprotein] in Fischer male rats fed 1 ppm of AB1 [aflatoxin B1] in a semipurified diet for 5 wk. A 20% cauliflower diet significantly reduced serum AFP and increased hepatic MFO [mixed function oxidase] activity. Apparently the lowered serum AFP predicts dietary cauliflower''s protective action against AB1-induced hepatocarcinoma.