MULTIPLE MYELOMA WITH SYNOVIAL AMYLOID DEPOSITION

Publisher Website
Google Scholar
Abstract
A 56-year-old man developed multiple myeloma with severe joint stiffness and arthralgia without definite joint swelling. At post-mortem examination large amounts of amyloid were found by light and electron microscopy in the synovial fluid and on the surface of the synovial membrane. Smaller amounts of amyloid were identified beneath the lining cells and in vessel walls. No inflammatory reaction was found in the synovial membrane or fluid. Synovial amyloid may occasionally be responsible for joint stiffness and arthralgia, as well as for more marked joint changes mimicking rheumatoid arthritis. The diagnosis can be established by synovial biopsy.

This publication has 0 references indexed in Scilit: