A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster
- 9 August 2005
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 65 (3) , 444-447
- https://doi.org/10.1212/01.wnl.0000168259.94991.8a
Abstract
This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.Keywords
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