First experience in the use of bone marrow mesenchymal stem cells for the treatment of a patient with deep skin burns
- 1 January 2005
- journal article
- case report
- Published by Springer Nature in Bulletin of Experimental Biology and Medicine
- Vol. 139 (1) , 141-144
- https://doi.org/10.1007/s10517-005-0232-3
Abstract
Female patient with extensive skin burn (I-II-IIIAB skin burn, total area 40%, area of IIIB degree 30%) was treated using transplantation of allogenic fibroblast-like bone marrow mesenchymal stem cells onto the surface of deep thermal burn. The study of wound healing dynamics after transplantation of allogenic fibroblast-like mesenchymal stem cells confirmed high tempo of wound regeneration in the presence of active neoangiogenesis. Due to this, autodermoplasty of burn wounds could be carried out with good results as early as on day 4 after transplantation of fibroblast-like mesenchymal stem cells; this led to more rapid healing of donor zones and accelerated rehabilitation of the patient.Keywords
This publication has 7 references indexed in Scilit:
- STIMULATORY EFFECTS OF CARTILAGE-DERIVED MORPHOGENETIC PROTEINS 1 AND 2 ON OSTEOGENIC DIFFERENTIATION OF BONE MARROW STROMAL CELLSCytokine, 2000
- Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cellsJournal of Cellular Physiology, 2000
- Human Bone Marrow Stromal Cell: Coexpression of Markers Specific for Multiple Mesenchymal Cell LineagesBlood Cells, Molecules, and Diseases, 2000
- Multilineage Potential of Adult Human Mesenchymal Stem CellsScience, 1999
- Isolation of Putative Progenitor Endothelial Cells for AngiogenesisScience, 1997
- Effect of Basic Fibroblast Growth Factor (bFGF) and Insulin-Like Growth Factors Type I (IGF-I) and Type II (IGF-II) on Adult Human Keratinocyte Growth and Fibronectin SecretionJournal of Investigative Dermatology, 1990
- Treatment of burns with cultured fibroblastsBulletin of Experimental Biology and Medicine, 1990