The Carcinogenicity for Mouse Skin and the Aromatic Hydrocarbon Content of Cigarette-Smoke Condensates2

Abstract
The carcinogenic activities of 2 cigarette tars, 1 prepared at New York University and 1 at Sloan-Kettering Institute, were compared by skin painting on mice under identical conditions. Cancers developed in 18 percent of the animals painted with SKI tar and in 8 percent of the animals painted with NYU tar. Chemical analysis of the 2 tars for 3 polynuclear aromatic hydrocarbons showed that the SKI tar possesses each of these compounds in concentrations 3 to 4 times as high as the NYU tar.

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