PUNCTURES OF THE BRAIN
- 1 July 1928
- journal article
- other
- Published by American Medical Association (AMA) in Archives of Neurology & Psychiatry
- Vol. 20 (1) , 1-13
- https://doi.org/10.1001/archneurpsyc.1928.02210130004001
Abstract
In a series of experimental punctures of the brain performed by one of us,1it was observed that, in addition to the usual scar composed of connective tissue and neuroglia, open tracks which did not contain any connective tissue and which were surrounded by little if any gliosis occasionally resulted. In the hope of explaining these variations, we have compared the result obtained from leaving injured brain tissue in place with the result following removal of an equal portion of such tissue. The investigation has thrown light on certain factors controlling gliosis and points to a fundamental principle involved in surgery of the brain. LITERATURE In general, the literature shows that wounds produced in experimental puncture of the brain have frequently been made by heated blunt needles (Tschistowitsch,2Coen,3Macklin and Macklin4and others). This produces a wide zone of injured tissue. The conclusions reached byKeywords
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