Syntheses of some α-D-ribofuranosylimidazoles related to purine nucleotide precursors

Abstract
5-Amino-1-α-D-ribofuranosylimidazole-4-carboxamide [the α-anomer of the nucleoside corresponding to AICAR (5-amino-1-β-D-ribofuranosylimidazole-4-carboxamide 5′-phosphate)] and a related 4-methoxycarbonyl compound have been synthesised from substituted ribofuranosyl azides possessing non-participating 2,3-cyclic carbonate protecting groups.
Keywords

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