Changes in probe sensitivity during nmr spectroscopic studies of the perfused rat heart: a warning
- 1 October 1992
- journal article
- other
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 27 (2) , 343-348
- https://doi.org/10.1002/mrm.1910270214
Abstract
During NMR experiments on isolated, perfused rat heart, we observed a 57% change in probe sensitivity when the perfusion buffer surrounding the heart was replaced by either a low‐ionic‐strength mannitol solution or air and the heart was made ischemic. Such changes in sensitivity, should they go unrecognized, would result in substantial quantification errors.Keywords
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