THE BONE MARROW

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Abstract
The improvement in the technic of biopsies of the bone marrow has added a valuable method to the diagnostic laboratory procedures to which the clinician can resort in the cases in which the examination of the peripheral blood fails to give definite information. The importance of the examination of the bone marrow in vivo becomes evident if one considers the fact that the circulating blood does not always reflect the condition of the bone marrow. Great differences exist sometimes between the cellular content of the blood and that of the bone marrow which may be the source of diagnostic errors. Since the biopsy of the bone marrow is expected to become widely used in clinical medicine, I shall present a brief discussion of the normal bone marrow and of the changes that are observed in some of the important disturbances of blood formation. THE NORMAL BONE MARROW In early

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