Diffusion Tensor MR Imaging of the Brain: Effect of Diffusion Weighting on Trace and Anisotropy Measurements

  • 8 December 2000
    • journal article
    • Vol. 21  (10) , 1813-1820
Abstract
BACKGROUND AND PURPOSE: In human brain, the relationship between MR signal and b value is complicated by cerebral perfusion, restricted diffusion, anisotropy, cellular membrane permeability, and active cellular transport of water molecules. Our purpose was to evaluate the effect of the number and strength of diffusion-sensitizing gradients on measured isotropic apparent diffusion coefficients (ADCi), fractional anisotropy (FA), and their respective SD in different anatomic locations of the brain.

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