Investigation of human plasma low density lipoprotein by three‐dimensional flourescence spectroscopy
- 31 March 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 198 (2) , 229-234
- https://doi.org/10.1016/0014-5793(86)80411-2
Abstract
Human plasma LDL exhibits a diffuse fluorescence (excitation 360 nm) in the 400–600 nm range. Application of three-dimensional fluorescence spectroscopy shows the presence of 7 fluorophores in the lipid and 6 fluorophores in the protein domain. The 430 nm fluorescence in freshly prepared LDL and its apo-B is most likely indicative for remnants of in vivo lipid peroxidation.Keywords
This publication has 8 references indexed in Scilit:
- Mapping of the total fluorescence of human blood serum as a new method for its characterizationAnalytica Chimica Acta, 1985
- Fluorescence quenching by iodide ions of low density lipoproteins from normolipidemic and hypercholesterolemic type IIa subjects. Effect of low density lipoprotein-cholesterol and low density lipoprotein non-apolipoprotein-BChemistry and Physics of Lipids, 1984
- Increased serum lipid peroxides initiate atherogenesisBioEssays, 1984
- Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1984
- Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.Proceedings of the National Academy of Sciences, 1984
- Spatial organization of low-density lipoproteins of the human aorta (a fluorescent probe study)Bulletin of Experimental Biology and Medicine, 1983
- Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomesBiochemical Journal, 1982
- Oxygen-mediated heterogeneity of apo-low-density lipoprotein.Proceedings of the National Academy of Sciences, 1978