Use of an Individual Unsaturated Lecithin from Yeast in Antigens for the Sero-Diagnosis of Syphilis

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Abstract
A pure unsaturated individual lecithin, L-alpha-(dipalmitoleyl)-lecithin, was tested as a component in cardiolipin antigens for the VDRL microflocculation test and the Kolmer complement-fixation test for syphilis and gave promising results. A pure saturated lecithin, L-alpha-(dipalmitoyl)-lecithin, prepared from the unsaturated forms above by hydrogenation, was also tested. Antigens containing it were successfully used in the Kolmer test but showed little or no reactivity in the VDRL test.