Constitutive Cardiac Overexpression of Sarcoplasmic/Endoplasmic Reticulum Ca 2+ -ATPase Delays Myocardial Failure After Myocardial Infarction in Rats at a Cost of Increased Acute Arrhythmias
- 20 April 2004
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 109 (15) , 1898-1903
- https://doi.org/10.1161/01.cir.0000124230.60028.42
Abstract
Background— Heart failure often complicates myocardial infarction (MI), and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA2a) is underexpressed in the failing myocardium. We examined the eff...Keywords
This publication has 16 references indexed in Scilit:
- Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overloadCardiovascular Research, 2003
- Dynamic Regulation of Sarcoplasmic Reticulum Ca2+ Content and Release by Luminal Ca2+-Sensitive Leak in Rat Ventricular MyocytesBiophysical Journal, 2001
- Mechanisms of Cardiomyocyte Dysfunction in Heart Failure Following Myocardial Infarction in RatsJournal of Molecular and Cellular Cardiology, 1998
- Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation.Journal of Clinical Investigation, 1997
- Differences in Expression of Sarcoplasmic Reticulum Ca2+-ATPase and Na+–Ca2+Exchanger Genes Between Adjacent and Remote Noninfarcted Myocardium After Myocardial InfarctionJournal of Molecular and Cellular Cardiology, 1997
- Interaction of Halothane with α- and β-Adrenoceptor Stimulations in Rat MyocardiumAnesthesiology, 1997
- Decreased expression of cardiac sarcoplasmic reticulum Ca2+-pump ATPase in congestive heart failure due to myocardial infarctionMolecular and Cellular Biochemistry, 1996
- Differential Effects of Thyroid Hormone on the Expression of Sarcoplasmic Reticulum Ca2+-ATPase Isoforms in Rat Skeletal Muscle FibersBiochemical and Biophysical Research Communications, 1994
- Myosin Light Chain Gene Expression Associated with Disease States of the Human HeartJournal of Molecular and Cellular Cardiology, 1993
- The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusionCardiovascular Research, 1988