The Antibacterial Activity of Quinolones against E. Coli: A Chemometric Study
- 1 January 1991
- journal article
- research article
- Published by Wiley in Quantitative Structure-Activity Relationships
- Vol. 10 (4) , 333-343
- https://doi.org/10.1002/qsar.19910100405
Abstract
A chemometric approach based on multivariate calibration and design in latent variables permits one to rationalize the antibacterial activity of quinolones against gram negative bacteria, ranking the relative importance of individual structural features, and suggesting a new active structure.Keywords
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