Effects of chemical modification on the L-glutamate receptors on the Onchidium neuron.

1 January 1983

journal article
research article
Published by Physiological Society of Japan in The Japanese Journal of Physiology

Vol. 33 (4) , 535-546
https://doi.org/10.2170/jjphysiol.33.535

Abstract

In the G-H cells of Onchidium esophageal ganglia, L-Glu elicited hyperpolarizations caused by an increase in K permeability. To identify the chemical groups of the structure of the L-Glu receptor, which is involved in the L-Glu response, the effects of chemical modifications were studied. Modifications of SH, guanidino, COOH or NH2 groups depressed L-Glu response. The modification of other polar amino acid residues and phospholipids did not have an effect on the L-Glu responses.

Keywords

GLUTAMATE RECEPTOR
CHEMICAL MODIFICATION

This publication has 1 reference indexed in Scilit:

Modification of arginine in the active sites of antibodies
Biochemistry, 1968