Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA
- 1 December 2002
- journal article
- Published by Springer Nature in The EMBO Journal
- Vol. 21 (23) , 6614-6624
- https://doi.org/10.1093/emboj/cdf637
Abstract
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.Keywords
This publication has 31 references indexed in Scilit:
- Nucleoside Analog Resistance Caused by Insertions in the Fingers of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involves ATP-Mediated ExcisionJournal of Virology, 2002
- Effects of Specific Zidovudine Resistance Mutations and Substrate Structure on Nucleotide-Dependent Primer Unblocking by Human Immunodeficiency Virus Type 1 Reverse TranscriptaseAntimicrobial Agents and Chemotherapy, 2002
- The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1Journal of Virology, 2002
- Cross-Linking of the Fingers Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase to Template-PrimerJournal of Virology, 2001
- Selective Excision of AZTMP by Drug-Resistant Human Immunodeficiency Virus Reverse TranscriptaseJournal of Virology, 2001
- Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNAThe EMBO Journal, 2001
- The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase 1 1Edited by A. R. FershtJournal of Molecular Biology, 2000
- Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acidsProceedings of the National Academy of Sciences, 1999
- Improved methods for building protein models in electron density maps and the location of errors in these modelsActa Crystallographica Section A Foundations of Crystallography, 1991
- Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition.Journal of Biological Chemistry, 1988