An Antifungal Naphthoquinone, Xanthones and Secoiridoids fromSwertia calycina
- 1 August 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 61 (04) , 362-364
- https://doi.org/10.1055/s-2006-958102
Abstract
A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.Keywords
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