19β → 28-Lactonization of Pomonic Acid from Lantana camara roots

Abstract
Lantana camara L. var. aculeata yielded a triterpenoid, pomonic acid (1). The acid-catalyzed lactonization of this γ-hydroxy acid afforded a rearranged lactone 3, the structure of which was as­ signed by detailed 2D-NMR studies. A reaction mechanism involving a 1,3-butadiene intermediate is proposed.

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